This month, our key scientists have reported a pre-clinical study in which the efficacy of photoimmunotherapy of esophageal cancer cell lines was enhanced by priming the cells after induction therapy of the receptor of interest, e.g. EGFR.
Hartmans E, Linssen MD, Sikkens C, Levens A, Witjes MJH, van Dam GM, Nagengast
WB. Tyrosine kinase inhibitor induced growth factor receptor upregulation enhances the efficacy of near-infrared targeted photodynamic therapy in esophageal adenocarcinoma cell lines. Oncotarget. 2017 May 2;8(18):29846-29856. doi: 10.18632/oncotarget.16165.